Speaker: Dr. Josep Puig, MD, PhD
Radiologist
Research Associate, Lecturer
University Hospital Dr. Josep Trueta (IDI) and Center of Comparative Medicine and Bio-imaging of Catalonia (CMCiB)
Girona and Badalona, Spain
Presentation title: Diffusion tensor imaging as a biomarker for stroke patients
We will review the technical fundamentals of DTI sequence and its role in predicting clinical recovery after stroke, with special interest on motor function, in monitoring treatment response, and in evaluating WM remodeling. We will critically appraise DTI studies and discuss their limitations, and we will explore directions for future study. Three main strategies to quantify stroke-related WM damage have been proposed: measuring fractional anisotropy distal to the stroke area, measuring the number of fibers that go through the stroke with tractography, and measuring the overlap between the stroke and a DTI map derived from healthy age- and gender-matched controls.