Radiomics and Advanced Neuroimaging in Neuro-oncology
Advanced neuroimaging techniques are increasingly important in the clinical management of brain tumors, enabling more accurate diagnosis, better surgical planning, and improved treatment monitoring. This webinar aims to provide radiologists with an overview of the clinical applications of perfusion MRI, advanced diffusion techniques, and volumetric imaging. Through practical examples and clinical cases, participants will learn how these tools can be integrated into daily practice to improve diagnostic precision and therapeutic decisions.
This webinar occurs in the past. You can watch the recording here.
This webinar occurs in the past. You can watch the recording here.
Program
- Introduction | Dr. Nahum Calvo Malvar (5 min)
- Perfusion MRI in Brain Tumors | Dr. Albert Pons-Escoda (15 min)
- Advanced Diffusion MRI | Dr. Pablo Naval-Baudin (15 min)
- Image Processing and Volumetry in Brain Tumors | Dr. Ignacio Martínez-Zalacaín (15 min)
- Live Q&A (15 min)
- Identify the clinical applications of perfusion magnetic resonance imaging (MRI) for tumor characterization and treatment monitoring.
- Learn about advanced diffusion techniques, including models beyond diffusion tensor imaging (DTI), useful for pre-surgical planning.
- Apply practical methodologies for image processing and tumor volumetry, including tools and strategies that facilitate clinical implementation.
- Understand the clinical value of perfusion and diffusion MRI in brain tumors.
- Get practical insights into image processing and volumetry techniques.
- Learn how to go beyond visual analysis with quantitative imaging.
- Participate in the live Q&A to address your questions directly with the experts.
Information on Speakers and Presentations
Moderator & Speaker: Dr. Nahum Calvo Malvar, MD, PhD Clinical Director of Diagnostic Imaging
Hospital Universitari de Bellvitge (ICS-IDI)
Barcelona, Spain
Hospital Universitari de Bellvitge (ICS-IDI)
Barcelona, Spain
Speaker: Dr. Albert Pons-Escoda, MD Consultant Radiologist, Neuroradiology Division
Hospital Universitari de Bellvitge (ICS-IDI)
Barcelona, Spain
Presentation: Perfusion MRI in Brain Tumors
Perfusion MRI, particularly dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI), is a powerful tool in the assessment of brain tumors, providing insights into tumor vascularity and hemodynamics. This presentation will delve into the principles of DSC-PWI, emphasizing the importance of acquisition parameters and post-processing techniques in obtaining reliable perfusion metrics. Dr. Pons-Escoda will discuss various perfusion parameters, such as relative cerebral blood volume (rCBV) and percentage of signal recovery (PSR), and their roles in tumor grading and differentiation. The session will also explore advanced analytical methods, including voxel-wise analysis and deep learning approaches, that enhance the diagnostic accuracy of perfusion MRI. Clinical applications will be illustrated through case studies, demonstrating how perfusion MRI can inform treatment planning and prognostication in neuro-oncology. Attendees will gain a comprehensive understanding of the current capabilities and future directions of perfusion imaging in the management of brain tumors.
Learning objectives:
Hospital Universitari de Bellvitge (ICS-IDI)
Barcelona, Spain
Presentation: Perfusion MRI in Brain Tumors
Perfusion MRI, particularly dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI), is a powerful tool in the assessment of brain tumors, providing insights into tumor vascularity and hemodynamics. This presentation will delve into the principles of DSC-PWI, emphasizing the importance of acquisition parameters and post-processing techniques in obtaining reliable perfusion metrics. Dr. Pons-Escoda will discuss various perfusion parameters, such as relative cerebral blood volume (rCBV) and percentage of signal recovery (PSR), and their roles in tumor grading and differentiation. The session will also explore advanced analytical methods, including voxel-wise analysis and deep learning approaches, that enhance the diagnostic accuracy of perfusion MRI. Clinical applications will be illustrated through case studies, demonstrating how perfusion MRI can inform treatment planning and prognostication in neuro-oncology. Attendees will gain a comprehensive understanding of the current capabilities and future directions of perfusion imaging in the management of brain tumors.
Learning objectives:
- Understand the impact of acquisition and processing parameters on perfusion MRI outcomes.
- Interpret key perfusion metrics and their clinical significance in brain tumor evaluation.
- Explore advanced techniques, such as voxel-wise analysis to enhance diagnostic precision.
Speaker: Dr. Pablo Naval-Baudin, MD Neuroradiologist, Department of Radiology
Hospital Universitari de Bellvitge
Barcelona, Spain
Presentation: Advanced Diffusion MRI
Advanced diffusion MRI techniques offer deep insights into tumor microstructure, heterogeneity, and white matter tract involvement—critical aspects in neuro-oncology. Yet, many of these tools remain underused in clinical practice. This talk will introduce a broad overview of available diffusion models and image processing techniques, from distortion correction (e.g., Topup and Eddy) to high angular resolution diffusion imaging (HARDI) and crossing fiber models such as constrained spherical deconvolution (CSD). Dr. Naval-Baudin will highlight how relying solely on conventional DTI and ignoring these advances can lead to suboptimal surgical planning. The session aims to bridge the gap between research-grade diffusion imaging and routine clinical practice.
Learning objectives:
Hospital Universitari de Bellvitge
Barcelona, Spain
Presentation: Advanced Diffusion MRI
Advanced diffusion MRI techniques offer deep insights into tumor microstructure, heterogeneity, and white matter tract involvement—critical aspects in neuro-oncology. Yet, many of these tools remain underused in clinical practice. This talk will introduce a broad overview of available diffusion models and image processing techniques, from distortion correction (e.g., Topup and Eddy) to high angular resolution diffusion imaging (HARDI) and crossing fiber models such as constrained spherical deconvolution (CSD). Dr. Naval-Baudin will highlight how relying solely on conventional DTI and ignoring these advances can lead to suboptimal surgical planning. The session aims to bridge the gap between research-grade diffusion imaging and routine clinical practice.
Learning objectives:
- Discover the wide range of diffusion models and preprocessing techniques available for imaging.
- Understand what is currently missing in clinical diffusion imaging workflows and the clinical implications of adopting (or ignoring) these techniques.
Speaker: Dr. Ignacio Martínez-Zalacaín, PhD Radiomics Department Coordinator
Hospital Universitari de Bellvitge
Barcelona, Spain
Presentation: Image Processing and Volumetry in Brain Tumors
Accurate image processing and volumetric analysis are critical for the assessment and management of brain tumors. This presentation will cover fundamental techniques of image preprocessing, including brain extraction, coregistration, and bias correction, which are essential for ensuring the quality and reliability of imaging data. Dr. Martínez-Zalacaín will discuss both manual and automated segmentation methods, highlighting the advantages and limitations of each approach. The session will also explore the application of deep learning algorithms, such as neural networks, in the segmentation and volumetric analysis of brain tumors. Furthermore, the relevance of volumetric measurements in clinical decision-making and their alignment with standardized assessment criteria, such as RANO 2.0, will be examined. Attendees will gain insights into the practical implementation of these techniques and their potential to enhance diagnostic accuracy and treatment planning in neuro-oncology.
Learning objectives:
Hospital Universitari de Bellvitge
Barcelona, Spain
Presentation: Image Processing and Volumetry in Brain Tumors
Accurate image processing and volumetric analysis are critical for the assessment and management of brain tumors. This presentation will cover fundamental techniques of image preprocessing, including brain extraction, coregistration, and bias correction, which are essential for ensuring the quality and reliability of imaging data. Dr. Martínez-Zalacaín will discuss both manual and automated segmentation methods, highlighting the advantages and limitations of each approach. The session will also explore the application of deep learning algorithms, such as neural networks, in the segmentation and volumetric analysis of brain tumors. Furthermore, the relevance of volumetric measurements in clinical decision-making and their alignment with standardized assessment criteria, such as RANO 2.0, will be examined. Attendees will gain insights into the practical implementation of these techniques and their potential to enhance diagnostic accuracy and treatment planning in neuro-oncology.
Learning objectives:
- Understand the essential steps in image preprocessing for brain tumor analysis.
- Compare manual and automated segmentation techniques and their clinical applications.
- Explore the integration of deep learning methods in volumetric analysis of brain tumors.
- Recognize the importance of volumetric data in adhering to standardized assessment protocols like RANO 2.0.
Discover More About the Speaker
Discover More About the Moderator and Speakers
Dr. Nahum Calvo MalvarDr. Nahum Calvo Malvar is the Clinical Director of Diagnostic Imaging at Hospital Universitari de Bellvitge, where he leads the strategic and operational management of radiology services across the hospital and its healthcare territory. After obtaining his medical degree from the University of Santiago de Compostela and completing his radiology residency at Hospital POVISA in Vigo, he earned his PhD from Universitat Rovira i Virgili with the distinction of cum laude. Early in his career, his clinical focus was on abdominal and hepatic imaging, including oncologic interventional radiology. Over time, his professional interests evolved towards team leadership, organizational management, and the implementation of innovative technologies in medical imaging. Dr. Calvo Malvar leads department’s digital transformation, promoting the integration of radiomics and advanced imaging analytics to enhance clinical workflows and precision diagnostics.
Dr. Albert Pons-EscodaDr. Albert Pons-Escoda is a Senior Consultant in Clinical Neuroradiology at the University Hospital of Bellvitge. Despite his full-time clinical dedication, he maintains a strong academic profile with a special focus on advanced MRI for brain tumor imaging. He has authored over 50 indexed scientific publications—more than 20 between 2023 and 2025 alone, including over 10 as first author—in high-impact journals. His scientific contributions have earned him several prestigious awards, including the European Society of Neuroradiology (ESNR) Scientific Award 2024. He is actively involved in several competitive research projects in neuro-oncology, advanced imaging, and radiogenomics. Albert also plays a leading academic role as the Spanish national delegate for the ESR Research Committee and as a senior scientific editorial board member of European Radiology. He is a frequently invited speaker at both national and international congresses and is currently serving on the scientific organizing committees for major upcoming international neuroradiology meetings.
Dr. Pablo Naval-BaudinDr. Pablo Naval-Baudin is a neuroradiologist at Hospital Universitari de Bellvitge in Barcelona, Spain. He has a strong interest and extensive experience in image analysis, image processing, and quantitative imaging techniques. His expertise encompasses both research applications, particularly in white matter diseases such as multiple sclerosis, and clinical applications, including diffusion imaging and functional MRI (fMRI) for neurosurgical planning. Dr. Naval-Baudin has contributed to numerous peer-reviewed publications in these areas. He is actively involved in resident education as a tutor and engages in research related to advanced neuroimaging methods.
Dr. Ignacio Martínez-ZalacaínDr. Ignacio Martínez-Zalacaín is a telecommunications engineer with a PhD in Medicine and Translational Research-Neuroscience. With over 14 years of experience in advanced quantitative image analysis, he currently coordinates the Radiomics Project within the Radiology Department at Hospital Universitari de Bellvitge in Barcelona, Spain. In this role, Dr. Martínez-Zalacaín oversees the team and resources, managing data processes, imaging analysis, and ensuring the scientific rigor of various projects. His expertise includes developing and applying multimodal neuroimaging techniques to investigate neural mechanisms underlying brain-related conditions. Dr. Martínez-Zalacaín has contributed to numerous peer-reviewed publications in the field of neuroimaging. He is actively involved in collaborative research projects and is a member of international consortia, which aim to enhance neuroimaging analyses through large-scale data sharing.
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